Clinical study

Does administration of the Transmuscular Quadratus lumborum block cause quadriceps muscle weakness? – A randomised, double-blinded volunteer study

  • Research area: Regional blockade

  • Primary investigator: Katrine Tanggaard

A randomised, double-blinded volunteer study

A randomised controlled double-blinded study including healthy volunteers focusing on the ability to mobilise following administration of a unilateral TQL block (compared to placebo, participant are their own control). Primary outcome will be change in quadriceps strength before and after block administration. Secondary outcomes will be an eventual change in: (1) Timed Up and Go, (2) 6 meter single leg jump test, (3) Dermatomal anaesthesia following administration of a unilateral TQL block (measured by controlled assessment of sensation to cold stimuli and pin-prick test). All participants will also have blood samples taken to analyse for ropivacaine serum concentrations. Our primary hypothesis is, that we will not find any significant weakness in quadriceps strength. The study is on going. Clinical Trials: NCT05023343