Clinical study

Multimodal pain treatment for breast cancer surgery – a prospective cohort study

  • Research area: Postoperative pain

  • Primary investigator: Anne Sofie Nautrup Therkelsen

A prospective cohort study of a minimum of 250 breast cancer patients planned for breast-conserving surgery or mastectomy. 

Breast cancer is one of the most common types of cancer among women worldwide. Breast-conserving surgery or mastectomy is indicated for the majority of the patients, but postoperative pain is frequent, with almost 50 % experiencing acute pain and 25-60 % reporting chronic pain.
Today no golden standard for postoperative pain management regarding breast cancer surgeries exists. Considering the large population and consequences of acute and chronic pain, such as prolonged recovery and affected quality of life, there is room for improvement.
We aim to evaluate a new standardised multimodal postoperative pain and anti-emetic regimen for patients undergoing day-case breast-conserving surgery or mastectomy with or without axillary lymph node dissection (ALND) or sentinel lymph node biopsy (SLNB). The study will focus on acute pain, postoperative nausea and vomiting (PONV), and quality of recovery during a seven-day postoperative follow-up period.